She may be reaching her 40’s, but she is still stunning as ever. The good thing about her beauty is that you won’t get tired of it. She looks really simple but still gorgeous. She has been in a long running TV show, Grey’s Anatomy, but prior to that, she has starred in several films. Among her box office hits are 27 Dresses, Life as We Know It and Knocked Up. Even before the other big names on this list arrived, there already was a Katherine Heigl.