Debra Messing
In her late 40’s, this former Will and Grace star is still a stunner. Since her comedy show ended in 2006, she went on to star in many other shows and movies. This includes The Starter Wife, Smash and Like Sunday, Like Rain. She is also the current leading lady of the show, The Mysteries of Laura. During her stint in Will and Grace, she has received quite a few awards for her performance. The good news is that there are reports that their show will be back on TV soon.